While there is limited clinical research, physicians do prescribe cannabis and cannabinoids to their patients.
The use of cannabis for medical treatment, however, has suggestive preliminary evidence that proves that it can reduce nausea and even fight back chronic pains and muscle spasms.
It is, however, important to note here that the cannabis plant has a long history of medicinal use that dates back to thousands of years in many cultures.
According to a recent study by Statista.com, a 77% increase in public approval of medical marijuana in the US was reported since 2011. Today 34 states approve of its medicinal use after California first passed a proposition to legalize it for medical purposes in 1996.
Furthermore, many states reported an increase in medicinal marijuana use in 2020. Around $7.1 billion retail sales were reported in the US during 2020 with over 28,000 businesses as of 2017 and the projected consumer market is expected to reach $37.3 billion in 2024.
In light of this information, let’s take a quick look at some of the ways through which medical use of marijuana can help cure health problems.
According to a study by the University of California, Los Angeles, Dronabinol, which is the oral form of marijuana was approved for appetite stimulation. In this study, endocannabinoid anandamide was proven to stimulate food intake in test subjects, and in another observation, a relationship between ghrelin and CB1 antagonists was discovered.
However, the variability of Dronabinol’s absorption is now leading researchers to believe that smoking marijuana would be more effective instead. This is due to the fact that the discovery of endocannabinoids and their receptors has drawn attention from the research community.
Marijuana may play a critical role in appetite stimulation through the leptin pathway. This can also lead towards other fields such as the prevention of obesity and its treatment. However, side effects such as psychosis have to be minimized, and this will make it a truly valuable treatment for appetite suppression.
Millions of Americans have been observed living with Alzheimer’s disease, where the symptoms can first appear after 60 years of age. While young people can also suffer from the ailment, however, it is much less common.
According to a study published by the US National Library of Medicine, results confirmed that CBD (Cannabidiol) along with THC (Tetrahydrocannabinol) was found to be effective in memory treatment.
This finding was based on the accumulated research of 1,149 studies, where only nine studies were selected in the final process and deemed appropriate for meeting selection criteria. Four out of five in vitro studies included the use of CBD on PC12 neuronal cells.
Furthermore, the study also concluded that CBD+THC treatment was found to be more effective than CBD alone and THC alone treatment.
CBD was observed to activate the peroxisome proliferator receptor. It happens through the catenin pathway which protects PC12 cells from neurotoxicity and oxidation stress.
Oncologists are medical professionals who practice oncology which is the branch of medicine that deals with the diagnosis, prevention, and treatment of cancer. According to a nationally representative survey study published by the Journal of Clinical Oncology®, 80% of medical oncologists sat down to discuss the use of medical marijuana with cancer patients.
This survey was carried out through the collection of responses from 400 medical oncologists, where bivariate and multivariate analyses were performed using standard statistical techniques.
While the response rate was 63%, only one-third of oncologist felt that they had been sufficiently informed to make recommendations.
Furthermore, 67% considered the use of marijuana as a helpful adjunct to standard pain management strategies, while 65% considered medical marijuana to be more effective than standard treatments of cachexia and anorexia induced by cancer.
Chronic Pain & Muscle Spasms
States across the US, including Alaska, Connecticut, Massachusetts, and Pennsylvania, allow the use of medical cannabis for muscle spasms caused by underlying conditions and muscle cramps. According to a study by the NCBI (National Center for Biotechnology Information), people suffering from multiple sclerosis and spinal cord injuries have sought relief through marijuana.
This study also included findings from a 1982 survey of 43 respondents out of which 21 reported that marijuana usage resulted in reduced muscle spasticity. Additionally, in a 1997 survey of 112 regular marijuana users with multiple sclerosis were observed to have lessened pain and spasticity.
Cannabinoid receptors in your ECS (Endocannabinoid System) bind with THC and CBD to start an anti-inflammatory response. This causes inflammation to be prevented and reduce muscle spasm after injury. In other studies, it was also found that THC and CBD reduce phenotype responsible for inflammation in multiple sclerosis.
Crohn’s disease causes a chronic condition that includes inflammation in the parts of the digestive tract and is considered to be a type of IBD (Inflammatory Bowel Disease). Symptoms include abdominal pain, cramping, diarrhea, fatigue, loss of appetite, nausea, and weight loss. An original March 2019 study published by Springer Link, concluded that cannabis consumption proved to mitigate several of the well-defined complications that comprise Crohn’s disease amongst inpatients.
The method of the study involved the collective data of 615 cannabis users that were compared directly after propensity score was matched to non-users. Various aspects of numerous complications and clinical end-points were included in the study.
Furthermore, the study also found that marijuana users and non-users were less likely to have an active fistulizing disease or intra-abdominal abscess. Plus cannabis users were also found to be less likely in need for a blood product transfusion, colectomy, or parenteral nutrition.
An extremely rare and drug-resistant form of epilepsy, the Dravet Syndrome begins in the first year of life in an otherwise healthy infant. Unfortunately, this is a lifelong ailment where patients often experience prolonged seizures along with feverish effects on one side of the body.
Most classes of Dravet Syndrome are caused by severe SCN1A gene mutations. In June 2018 FDA announced their approval of marijuana in their new release for the treatment of Dravet Syndrome.
It is important to note here that controlled clinical trials involving 516 patients with Dravet syndrome were conducted to study the effectiveness of Epidiolex along with other medications.
This goes to show that researchers are encouraged to advance their understanding of the sound development of programs that can evaluate active ingredients contained in marijuana for their future studies for the development of important medical therapies. Students suffering from DS and seeking help from professional dissertation writers UK also take medical marijuana occasionally to treat their symptoms.
An eye condition group, Glaucoma causes damage to the optic nerve, which is vital for good vision. The damage is caused by abnormally high pressure in the eyes and Glaucoma itself is considered one of the leading causes of blindness for people over the age of 60 years.
According to a study published by the National Institutes of Health, several clinical researchers found that cannabinoids or marijuana were able to reduce IOP (intraocular pressure) as well as compared to conventional glaucoma medications produced synthetically in laboratories.
The clinical evaluations included in the study observed that the use of cannabinoids and marijuana reduced intraocular pressure (IOP) significantly in patients. Furthermore, in most trials, a single dose maintained beneficial effects for up to three to four hours.
However, this holds true only when cannabinoids are administered intravenously or orally. Also, when the act is done through inhalation, but not when it is applied directly to the eye. Students with Glaucoma often request experts to write my essay when their symptoms feel uncontrollable.
LGS (Lennox-Gastaut Syndrome) is a type of epilepsy where patients experience different types of seizures, including stiffening of the body, temporary loss of muscle tone, loss of consciousness, and staring episodes.
On June 25, 2018, the FDA approved the use of Epidiolex (cannabidiol) [CBD] as an oral solution. They approved it for the treatment of seizures. Particularly seizures associated with severe forms of ellipse such as Lennox-Gastaut Syndrome in their news release.
Billy Dunn, M.D., and the Director of the Division of Neurology Products in the FDA’s Center for Drug Evaluation and Research proclaimed that the approval of the drug would provide significant improvement in the therapeutic approach to caring for patients.
However, while cannabidiol is approved, it is important to mention that no single medication can completely resolve seizures. This is why, apart from medical support, monitoring from a doctor and emotional support from parents is considered mandatory.
According to a personal study by Meg Lewellyn published by Healthline, she was able to see long-term benefits for using medical marijuana as a treatment of her MS ailments that was diagnosed in 2007. Multiple sclerosis is a chronic inflammatory and neurodegenerative disease that affects over 400,000 people in the US and over 2.1 million people worldwide.
It is a potentially disabling disease of the spinal cord and the brain where the immune system starts attacking the myelin (protective sheath) which is covering the nerve fibers. Due to this, communication problems between your brain and rest of your body occur.
Today after years of research and studies, medical cannabis is made available to be administered through various methods. This includes cannabis edibles, capsules, dermal patches, dermal sprays, smoking dried buds, and tinctures, to name a few. I hope this post was able to provide you with some meaningful insights as to how cannabis can be used to help find health cures.
Author Bio: Claudia Jeffrey currently works as an Assistant Manager for Research & Development at King Essay and Crowd Writer. This is where higher education students can acquire assignment writing service UK from professionals specializing in their field of study. During her free time, she likes to go for long walks on the beach with her pet terrier.